I would suggest making the signs in photoshop or any other computer program then bringing them to the department and printing them out on the color or laser printer. I'd shoot for making the signs look about the same from a distance with funnier content.

Signs to make

Zero Gravity Toilet

Get creative with this. The actual text is here but it might be funnier to do different words with the same basic sign layout.

Emergency Revival Procedure

Again get creative and maybe customize to each professor without being too mean. These will go on the profs doors. Work on the sign and text and we'll put it together with the rest of the panel and blue buttons made out of construction paper

Vitals Readout

I think all we need in advance here are the labels on the left on the colored squares which we can then glue to black construction paper to make the rest of the panel. We have a pen to draw the rest (other than the labels) on the black paper.

Caution Explosive Bolts

I have no idea what the little black lettering between "Maintenence and Repair Instructions" and "Explosive Bolts" says. Make something up the is funny

RED Caution Explosive Bolts

This one would probably kill the red on our printer so it is probably better to make it by cutting out white letters to glue on red construction paper. Not sure if we need this sign anyway if we have the other one.

Logic Memory Center

This is going on the door in the computer room. I'm thinking that we put a red piece of 8.5x11 construction paper between two white pieces of the same size. The lettering and white lines on the red construction paper can be done with the pen we've got. If we could make the white portions of the sign on the right and the left in photoshop that I think would be the way to go.

Assorted Props

Cockpit of Earth to Spacestation ship

Memory Blocks in HAL Memory core

Cockpit of Spacestation to Moon ship

Airline food on Earth-Moon trip

Food dispenser on Discovery

Block-o-food eaten on Discovery

Hibernation chambers

Single hibernation chamber with panel

HAL main console

AE35 repair spacewalk

Grip for opening emergency airlock

Second perspective of emergency airlock

Emergency hatch close